Effects of hydroalcoholic extract of <i>Borago officinalis</i> on naloxone-precipitated withdrawal syndrome in morphine-dependent mice
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چکیده
منابع مشابه
COMPARISON OF ACUTE AND CHRONIC EFFECTS OF NIFEDIPINE ON NALOXONE-PRECIPITATED MORPHINE WITHDRAWAL IN MICE
Mice were rendered tolerant and dependent to morphine by subcutaneous injection of morphine over a period of 5 days. The effects of acute and chronic administration of dihydropyridine calcium channel antagonist nifedipine on the development of tolerance and naloxone-precipitated morphine withdrawal signs were investigated. A single injection of nifedipine proved to be effective in inhibiti...
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There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of morphine dependence. In this study, the effects of acute and chronic administration of nitrendipine on naloxone precipitated morphine withdrawal signs were investigated. Mice were rendered dependent to morphine by subcutaneous injection of morphine over a period of 5 days. In chronic s...
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This research was done to test the effect of Rosa damascena essential oil on withdrawal signsof naloxone-precipitated morphine in male mice. Morphine dependence was induced by injection(IP) three times daily at doses of 50, 50 and 75 mg/kg, respectively, for 3 days. On day 4,after the last administration of morphine, Rosa damascena essential oil was administered atdifferent concentrations (5, 2...
متن کاملAcute and Chronic Effects of Nitrendipine on Naloxone Precipitated Morphine Withdrawal in Mice
There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of morphine dependence. In this study, the effects of acute and chronic administration of nitrendipine on naloxone precipitated morphine withdrawal signs were investigated. Mice were rendered dependent to morphine by subcutaneous injection of morphine over a period of 5 days. In chronic s...
متن کاملSuppressive Effects of Rosa Damascena Essential Oil on Naloxone-Precipitated Morphine Withdrawal Signs in Male Mice
This research was done to test the effect of Rosa damascena essential oil on withdrawal signsof naloxone-precipitated morphine in male mice. Morphine dependence was induced by injection(IP) three times daily at doses of 50, 50 and 75 mg/kg, respectively, for 3 days. On day 4,after the last administration of morphine, Rosa damascena essential oil was administered atdifferent concentrations (5, 2...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2016
ISSN: 1991-0088
DOI: 10.3329/bjp.v11i4.26915